[54] LSU 17-31 Mississippi [24] 2021-10-23 19:30
Stadium: Vaught-Hemingway Stadium Round: 1
Home Manager: Lane Kiffin Away Manager: Ed Orgeron
Head to Head
| NCAAF | 2020/12/19 20:30 | Mississippi v LSU | W | 48-53 |
| NCAAF | 2019/11/17 00:00 | LSU v Mississippi | W | 58-37 |
| NCAAF | 2018/09/30 01:15 | Mississippi v LSU | W | 16-45 |
| NCAAF | 2017/10/21 23:15 | LSU v Mississippi | W | 40-24 |
| NCAAF | 2016/10/23 01:00 | Mississippi v LSU | W | 21-38 |
| NCAAF | 2015/11/21 20:30 | Mississippi v LSU | L | 38-17 |
| NCAAF | 2014/10/25 23:15 | LSU v Mississippi | W | 10-7 |
| NCAAF | 2012/11/17 12:00 | LSU v Mississippi | W | 41-35 |
| NCAAF | 2011/11/19 12:00 | Mississippi v LSU | W | 3-52 |
| NCAAF | 2010/11/20 12:00 | LSU v Mississippi | W | 43-36 |
| NCAAF | 2009/11/21 12:00 | Mississippi v LSU | L | 25-23 |
| NCAAF | 2008/11/22 12:00 | LSU v Mississippi | L | 13-31 |
| NCAAF | 2007/11/17 12:00 | Mississippi v LSU | W | 24-41 |
| NCAAF | 2006/11/18 12:00 | LSU v Mississippi | W | 23-20 |
| NCAAF | 2005/11/19 12:00 | Mississippi v LSU | W | 7-40 |
| NCAAF | 2004/11/20 12:00 | LSU v Mississippi | W | 27-24 |
| NCAAF | 2003/11/22 12:00 | Mississippi v LSU | W | 14-17 |
| NCAAF | 2002/11/23 12:00 | LSU v Mississippi | W | 14-13 |
| NCAAF | 2001/10/27 12:00 | LSU v Mississippi | L | 24-35 |
| NCAAF | 2000/11/11 12:00 | Mississippi v LSU | W | 9-20 |
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