[80] USC 16-31 Notre Dame [27] 2021-10-23 23:30
Stadium: Notre Dame Stadium Round: 1
Home Manager: Brian Kelly Away Manager: Donte Williams
Head to Head
| NCAAF | 2019/10/12 23:30 | USC v Notre Dame | L | 27-30 |
| NCAAF | 2018/11/25 01:00 | Notre Dame v USC | L | 24-17 |
| NCAAF | 2017/10/21 23:30 | USC v Notre Dame | L | 14-49 |
| NCAAF | 2016/11/26 20:30 | Notre Dame v USC | W | 27-45 |
| NCAAF | 2015/10/17 23:30 | Notre Dame v USC | L | 41-31 |
| NCAAF | 2014/11/29 20:30 | USC v Notre Dame | W | 49-14 |
| NCAAF | 2012/11/24 12:00 | USC v Notre Dame | L | 13-22 |
| NCAAF | 2011/10/22 12:00 | Notre Dame v USC | W | 17-31 |
| NCAAF | 2010/11/27 12:00 | USC v Notre Dame | L | 16-20 |
| NCAAF | 2009/10/17 12:00 | Notre Dame v USC | W | 27-34 |
| NCAAF | 2008/11/29 12:00 | USC v Notre Dame | W | 38-3 |
| NCAAF | 2007/10/20 12:00 | Notre Dame v USC | W | 0-38 |
| NCAAF | 2006/11/25 12:00 | USC v Notre Dame | W | 44-24 |
| NCAAF | 2005/10/15 12:00 | Notre Dame v USC | W | 31-34 |
| NCAAF | 2004/11/27 12:00 | USC v Notre Dame | W | 41-10 |
| NCAAF | 2003/10/18 12:00 | Notre Dame v USC | W | 14-45 |
| NCAAF | 2002/11/30 12:00 | USC v Notre Dame | W | 44-13 |
| NCAAF | 2001/10/20 12:00 | Notre Dame v USC | L | 27-16 |
| NCAAF | 2000/11/25 12:00 | USC v Notre Dame | L | 21-38 |
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