Stadium: Bragg Memorial Stadium Round: 1
Home Manager: Willie Simmons Away Manager: Oliver Pough
| NCAAF | 2018/10/27 17:00 | Howard v South Carolina State | W | 21-27 |
| NCAAF | 2018/10/20 17:30 | Delaware State v South Carolina State | W | 19-30 |
| NCAAF | 2018/10/13 18:00 | Bethune Cookman v South Carolina State | L | 28-26 |
| NCAAF | 2018/10/06 17:00 | South Carolina State v Morgan State | W | 21-18 |
| NCAAF | 2018/09/27 23:00 | South Carolina State v North Carolina A&T | L | 16-31 |
| NCAAF | 2018/09/22 22:00 | Norfolk State v South Carolina State | L | 17-7 |
| NCAAF | 2018/09/08 22:00 | South Carolina State v Central Florida | L | 0-38 |
| NCAAF | 2018/09/01 22:00 | South Carolina State v Georgia Southern | L | 6-37 |
| NCAAF FCS | 2018/11/03 17:00 | Florida A&M v Howard | L | 23-31 |
| NCAAF | 2018/10/27 20:00 | Florida A&M v Morgan State | W | 38-3 |
| NCAAF | 2018/10/13 17:00 | Florida A&M v North Carolina A&T | W | 22-21 |
| NCAAF | 2018/10/06 20:00 | Norfolk State v Florida A&M | W | 0-17 |
| NCAAF | 2018/09/29 20:00 | Florida A&M v North Carolina Central | W | 55-14 |
| NCAAF | 2018/09/22 22:00 | Savannah State v Florida A&M | W | 13-31 |
| NCAAF | 2018/09/15 21:00 | Jackson State v Florida A&M | L | 18-16 |
| NCAAF | 2018/09/08 23:00 | Florida A&M v Troy | L | 7-59 |