Stadium: Tucker Stadium Round: 1
Home Manager: Dewayne Alexander Away Manager: Mitch Stewart
| NCAAF | 2018/10/27 20:00 | Murray State v Jacksonville State | L | 15-42 |
| NCAAF | 2018/10/20 19:00 | Eastern Kentucky v Murray State | W | 6-34 |
| NCAAF | 2018/10/13 18:00 | Tennessee State v Murray State | W | 21-45 |
| NCAAF | 2018/10/06 23:00 | Murray State v Eastern Illinois | W | 48-41 |
| NCAAF | 2018/09/29 23:00 | Tennessee Martin v Murray State | W | 38-45 |
| NCAAF | 2018/09/15 16:00 | Murray State v Kentucky | L | 10-48 |
| NCAAF | 2018/09/08 23:00 | Murray State v Central Arkansas | L | 13-26 |
| NCAAF | 2018/08/30 23:00 | SO Illinois v Murray State | L | 49-10 |
| NCAAF | 2018/10/27 21:00 | Austin Peay v Tennessee Tech | L | 41-10 |
| NCAAF | 2018/10/20 21:30 | Tennessee State v Tennessee Tech | L | 41-14 |
| NCAAF | 2018/10/06 23:00 | SE Missouri St v Tennessee Tech | L | 70-38 |
| NCAAF | 2018/09/29 23:00 | Eastern Illinois v Tennessee Tech | L | 52-38 |
| NCAAF | 2018/09/22 23:00 | Tennessee Tech v Jacksonville State | L | 20-48 |
| NCAAF | 2018/09/14 00:00 | Tennessee Tech v Utah State | L | 12-73 |
| NCAAF | 2018/09/06 23:00 | Tennessee Tech v Kennesaw State | L | 10-49 |
| NCAAF | 2018/08/30 23:00 | Tennessee Tech v Tennessee Chattanooga | L | 10-34 |