Stadium: UNI-Dome Round: 1
Home Manager: Mark Farley Away Manager: Brock Spack
| NCAAF | 2018/10/27 17:00 | Illinois State v South Dakota State | L | 28-38 |
| NCAAF | 2018/10/20 19:30 | North Dakota State v Illinois State | L | 28-14 |
| NCAAF | 2018/10/13 19:00 | SO Illinois v Illinois State | W | 3-51 |
| NCAAF | 2018/10/06 19:00 | Western Illinois v Illinois State | W | 16-33 |
| NCAAF | 2018/09/29 19:00 | Illinois State v Missouri St | L | 21-24 |
| NCAAF | 2018/09/22 19:00 | Illinois State v Colorado State | W | 35-19 |
| NCAAF | 2018/09/08 23:30 | Eastern Illinois v Illinois State | W | 10-48 |
| NCAAF | 2018/09/01 23:30 | Illinois State v Saint Xavier Cougars | W | 46-0 |
| NCAAF | 2018/10/27 18:00 | Western Illinois v Northern Iowa | L | 37-17 |
| NCAAF | 2018/10/20 21:00 | Northern Iowa v South Dakota State | W | 24-9 |
| NCAAF | 2018/10/13 23:00 | Northern Iowa v South Dakota | W | 42-28 |
| NCAAF | 2018/10/06 18:00 | North Dakota State v Northern Iowa | L | 56-31 |
| NCAAF | 2018/09/27 23:00 | Northern Iowa v Indiana State | W | 33-0 |
| NCAAF | 2018/09/22 21:00 | Hampton v Northern Iowa | W | 0-44 |
| NCAAF | 2018/09/15 23:30 | Northern Iowa v Iowa | L | 14-38 |
| NCAAF | 2018/09/02 01:00 | Northern Iowa v Montana | L | 23-26 |