Stadium: Bailey Memorial Stadium Round: 1
Home Manager: Steve Englehart Away Manager:
| NCAAF | 2022/09/03 23:00 | Presbyterian v Austin Peay | L | 0-63 |
| NCAAF | 2021/11/20 19:00 | Presbyterian v St.Thomas MIN | L | 15-54 |
| NCAAF | 2021/11/13 18:00 | Marist v Presbyterian | L | 57-32 |
| NCAAF | 2021/11/06 18:00 | Presbyterian v Valparaiso | L | 55-65 |
| NCAAF | 2021/10/30 17:00 | Stetson Hatters v Presbyterian | L | 56-14 |
| NCAAF | 2021/10/23 17:00 | San Diego v Presbyterian | L | 69-28 |
| NCAAF | 2021/10/16 23:00 | Presbyterian v Davidson Wildcats | L | 35-70 |
| NCAAF | 2021/10/09 17:00 | Morehead State v Presbyterian | L | 38-30 |
| NCAAF | 2022/09/01 23:00 | Virginia Union Panthers v Lynchburg Dragons | L | 77-0 |
| NCAAF | 2021/10/23 18:30 | Tennessee Tech v Lynchburg Dragons | L | 56-13 |
| NCAAF | 2021/10/16 18:00 | Norfolk State v Lynchburg Dragons | L | 42-14 |
| NCAAF | 2021/10/09 18:00 | Delaware State v Lynchburg Dragons | L | 56-6 |
| NCAAF | 2021/10/02 18:00 | Erskine Flying Fleet v Lynchburg Dragons | L | 59-13 |
| NCAAF | 2021/09/25 17:00 | Duquesne v Lynchburg Dragons | L | 56-7 |
| NCAAF | 2021/09/18 22:00 | Virginia Union Panthers v Lynchburg Dragons | L | 49-7 |
| NCAAF | 2021/09/09 23:00 | Mars Hill Lions v Lynchburg Dragons | L | 50-14 |