Stadium: Barker-Lane Stadium Round: 1
Home Manager: Mike Minter Away Manager: Autry Denson
| NCAAF | 2021/10/30 17:00 | Campbell v Charleston Southern | W | 14-27 |
| NCAAF | 2019/11/23 20:30 | Campbell v Charleston Southern | W | 31-41 |
| NCAAF FCS | 2018/11/17 19:00 | Charleston Southern v Campbell | W | 12-7 |
| NCAAF | 2022/09/24 16:00 | Furman v Charleston Southern | L | 24-19 |
| NCAAF | 2022/09/17 22:00 | Charleston Southern v Eastern Kentucky | L | 17-40 |
| NCAAF | 2022/09/10 16:30 | Charleston Southern v NC State | L | 3-55 |
| NCAAF | 2022/09/03 16:00 | Western Carolina v Charleston Southern | L | 52-38 |
| NCAAF | 2021/11/20 17:00 | Charleston Southern v Georgia | L | 7-56 |
| NCAAF | 2021/11/13 18:30 | Charleston Southern v Gardner Webb | W | 32-24 |
| NCAAF | 2021/11/06 17:00 | North Carolina A&T v Charleston Southern | L | 21-18 |
| NCAAF | 2021/10/30 17:00 | Campbell v Charleston Southern | W | 14-27 |
| NCAAF | 2022/10/01 16:00 | Campbell v North Carolina Central | W | 48-18 |
| NCAAF | 2022/09/17 22:00 | Campbell v East Carolina | L | 10-49 |
| NCAAF | 2022/09/10 22:00 | Campbell v William & Mary | L | 21-37 |
| NCAAF | 2022/09/01 22:00 | The Citadel v Campbell | W | 10-29 |
| NCAAF | 2021/11/20 17:00 | Campbell v Robert Morris | L | 17-20 |
| NCAAF | 2021/11/13 18:00 | Hampton v Campbell | L | 28-21 |
| NCAAF | 2021/11/06 19:30 | Campbell v James Madison | L | 14-51 |
| NCAAF | 2021/10/30 17:00 | Campbell v Charleston Southern | L | 14-27 |