Stadium: Capital One Arena Round: 122
Home Manager: Ashley Howard Away Manager: Billy Lange
| NCAAB | 2022/03/03 00:00 | St. Josephs v La Salle | L | 48-49 |
| NCAAB | 2022/01/17 21:00 | La Salle v St. Josephs | L | 75-64 |
| NCAAB | 2021/03/03 16:00 | St. Josephs v La Salle | W | 72-66 |
| NCAAB | 2021/02/20 17:30 | La Salle v St. Josephs | W | 82-91 |
| NCAAB | 2021/01/18 21:00 | St. Josephs v La Salle | L | 83-90 |
| NCAAB | 2020/03/07 19:00 | La Salle v St. Josephs | L | 78-77 |
| NCAAB | 2020/02/08 22:00 | St. Josephs v La Salle | L | 66-83 |
| NCAAB | 2019/03/02 22:00 | La Salle v St. Josephs | W | 62-72 |
| NCAAB | 2022/03/05 19:30 | Rhode Island v St. Josephs | W | 60-70 |
| NCAAB | 2022/03/03 00:00 | St. Josephs v La Salle | L | 48-49 |
| NCAAB | 2022/02/26 23:00 | St. Bonaventure v St. Josephs | L | 54-52 |
| NCAAB | 2022/02/23 01:00 | St. Josephs v St. Louis | L | 61-72 |
| NCAAB | 2022/02/19 18:00 | Dayton v St. Josephs | L | 74-62 |
| NCAAB | 2022/02/17 00:00 | George Mason v St. Josephs | L | 75-70 |
| NCAAB | 2022/02/12 17:00 | St. Josephs v Massachusetts | L | 67-69 |
| NCAAB | 2022/02/10 00:00 | St. Josephs v Davidson | L | 67-73 |
| NCAAB | 2022/03/05 19:00 | La Salle v Duquesne | W | 85-76 |
| NCAAB | 2022/03/03 00:00 | St. Josephs v La Salle | W | 48-49 |
| NCAAB | 2022/02/26 19:00 | Dayton v La Salle | W | 60-62 |
| NCAAB | 2022/02/24 00:00 | La Salle v Fordham | L | 54-60 |
| NCAAB | 2022/02/19 17:00 | La Salle v Massachusetts | L | 74-80 |
| NCAAB | 2022/02/17 01:00 | La Salle v St. Louis | L | 64-90 |
| NCAAB | 2022/02/12 23:00 | La Salle v Richmond | L | 63-77 |
| NCAAB | 2022/02/09 00:00 | St. Louis v La Salle | L | 75-57 |